Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 2/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6667353 | 0.96 | POLA1 (0.57) | POLA1KCNH2F2MEN1KMT2A | |
| SCHEMBL6668377 | 0.93 | F2 (0.59) | POLA1KCNH2F2MEN1KMT2A | |
| SCHEMBL6697165 | 0.90 | F2 (0.60) | POLA1KCNH2F2MEN1KMT2A | |
| SCHEMBL6667644 | 0.89 | F2 (0.57) | POLA1KCNH2F2MEN1KMT2A | |
| SCHEMBL6670482 | 0.88 | KCNH2 (0.59) | POLA1KCNH2F2MEN1KMT2A | |
| SCHEMBL6694680 | 0.88 | POLA1 (0.60) | POLA1KCNH2F2MEN1KMT2A | |
| SCHEMBL6698352 | 0.87 | F2 (0.62) | POLA1KCNH2F2MEN1KMT2A | |
| SCHEMBL6668954 | 0.87 | KCNH2 (0.57) | POLA1KCNH2F2MEN1KMT2A | |
| SCHEMBL6693197 | 0.86 | KCNH2 (0.59) | POLA1KCNH2F2MEN1KMT2A | |
| SCHEMBL6697748 | 0.86 | KCNH2 (0.58) | POLA1KCNH2F2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | claimed |