SCHEMBL6668490

SCHEMBL6668490

Cc1c(N2CCC(C3(O)CC3)C2)c(F)cc2c(=O)[nH]c(=O)n(C3CC3)c12

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 12/20 0.51
SCN5A Q14524 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6674178 0.88 KCNH2 (0.64) KCNH2SCN5A
Hydrochloric Acid SCHEMBL7094190 0.88 KCNH2 (0.64) KCNH2SCN5A
SCHEMBL6671956 0.84 KCNH2 (0.44) KCNH2SCN5A
SCHEMBL7552911 0.84 KCNH2 (0.45) KCNH2SCN5A
SCHEMBL6670700 0.83 KCNH2 (0.47) KCNH2SCN5A
SCHEMBL6670694 0.83 KCNH2 (0.47) KCNH2SCN5A
SCHEMBL6669284 0.82 KCNH2 (0.40) KCNH2SCN5A
SCHEMBL6377855 0.82 KCNH2 (0.41) KCNH2SCN5A
SCHEMBL6669156 0.82 KCNH2 (0.40) KCNH2SCN5A
SCHEMBL6687424 0.81 KCNH2 (0.44) KCNH2SCN5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1401830-A2 QUINAZOLINEDIONES AS ANTIBACTERIAL AGENTS Warner-Lambert Company LLC (US) 2004-03-31 EP claimed
WO-2002102793-A2 QUINAZOLINEDIONES AS ANTIBACTERIAL AGENTS WARNER-LAMBERT COMPANY LLC (US) 2002-12-27 WO claimed