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Sugi Predict / Compounds / P-Toluenesulfonamide

P-Toluenesulfonamide

P-Toluenesulfonamide

SCHEMBL6669022

CCCCN(CCC1CCCCC1)Cc1ccc(C(=O)N[C@@H](CCSC)C(=O)O)c(-c2ccccc2C)c1.Cc1ccc(S(N)(=O)=O)cc1

nearest known ligand 0.85

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Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ FNTA P49354 1/20 0.85
▸ FNTB P49356 1/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL629301 0.92 FNTA (1.00) FNTAFNTB
SCHEMBL629302 0.92 FNTA (1.00) FNTAFNTB
P-Toluenesulfonamide SCHEMBL6645582 0.89 FNTA (0.66) FNTAFNTB
P-Toluenesulfonamide SCHEMBL6645570 0.89 FNTA (0.66) FNTAFNTB
P-Toluenesulfonamide SCHEMBL7870353 0.89 FNTA (0.66) FNTAFNTB
P-Toluenesulfonamide SCHEMBL7870326 0.89 FNTA (0.66) FNTAFNTB
SCHEMBL10192964 0.87 FNTA (0.89) FNTAFNTB
SCHEMBL629273 0.87 FNTA (0.89) FNTAFNTB
SCHEMBL10192950 0.86 FNTA (0.88) FNTAFNTB
SCHEMBL6625701 0.86 FNTA (0.71) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0986384-A4 INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES UNIV PITTSBURGH (US) 2004-09-15 — — EP claimed
EP-0986384-A1 INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES UNIVERSITY OF PITTSBURGH (US) 2000-03-22 — — EP claimed
US-6310095-B1 INHIBITING OR TREATING CANCER, TREATING INTIMAL HYPERPLASIA ASSOCIATED WITH RESTENOSIS AND ATHEROSCLEROSIS, INHIBITING POST-TRANSLATIONAL MODIFICATION OF ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE AND/OR GERANYLGERANYLTRANSFERASE UNIVERSITY OF PITTSBURGH 2001-10-30 — — US disclosed