SCHEMBL6669232

SCHEMBL6669232

CC(=O)Oc1cccc(-n2nnc(-c3ccccn3)n2)c1

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 20/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14424212 0.86 GRM5 (0.72) GRM5
SCHEMBL4699461 0.85 GRM5 (0.73) GRM5
SCHEMBL4698761 0.84 GRM5 (0.77) GRM5
SCHEMBL4701047 0.82 GRM5 (0.73) GRM5
SCHEMBL4704589 0.82 GRM5 (1.00) GRM5
SCHEMBL13683999 0.81 GRM5 (0.78) GRM5
SCHEMBL4698356 0.81 GRM5 (0.64) GRM5
SCHEMBL4701203 0.80 GRM5 (0.82) GRM5
SCHEMBL4701272 0.80 GRM5 (1.00) GRM5
SCHEMBL13683870 0.79 GRM5 (0.76) GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004030637-A2 TREATMENT OF OBESITY AND OTHER DISORDERS ASSOCIATED WITH EXCESSIVE FOOD INTAKE MERCK & CO., INC. (US) 2004-04-15 WO claimed