Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6667281 | 0.89 | DRD3 (0.51) | DRD3KDM4EALDH1A1HPGDHTT | |
| SCHEMBL6665776 | 0.89 | DRD3 (0.42) | DRD3KDM4EALDH1A1HPGDHTT | |
| SCHEMBL11391209 | 0.85 | DRD3 (0.62) | DRD3KDM4EALDH1A1HPGDHTT | |
| SCHEMBL5681002 | 0.85 | DRD3 (0.55) | DRD3KDM4EALDH1A1HPGDHTT | |
| SCHEMBL11027094 | 0.85 | DRD3 (0.64) | DRD3KDM4EALDH1A1HPGDHTT | |
| SCHEMBL6664468 | 0.83 | DRD3 (0.77) | DRD3KDM4EALDH1A1HPGDHTT | |
| SCHEMBL11386776 | 0.81 | DRD3 (0.63) | DRD3KDM4EALDH1A1HPGDHTT | |
| SCHEMBL10753542 | 0.80 | KDM4E (0.77) | DRD3KDM4EALDH1A1HPGDHTT | |
| SCHEMBL11396020 | 0.80 | DRD3 (0.62) | DRD3KDM4EALDH1A1HPGDHTT | |
| SCHEMBL11394725 | 0.80 | DRD3 (0.57) | DRD3KDM4EALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831845-B1 | DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS | ELIZANOR BIOPHARMACEUTICALS IN (US) | 2004-09-08 | — | — | EP | claimed |
| WO-1996040156-A1 | DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS | ELIZANOR BIOPHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | claimed |