Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5226255 | 0.91 | F10 (0.80) | F10 | |
| SCHEMBL6623156 | 0.89 | F10 (0.75) | F10 | |
| SCHEMBL5223662 | 0.86 | F10 (0.84) | F10 | |
| SCHEMBL5226132 | 0.84 | F10 (0.83) | F10 | |
| SCHEMBL5226588 | 0.83 | F10 (1.00) | F10 | |
| SCHEMBL5223184 | 0.81 | F10 (0.82) | F10 | |
| SCHEMBL5223266 | 0.81 | F10 (0.89) | F10 | |
| SCHEMBL5224018 | 0.80 | F10 (0.85) | F10 | |
| SCHEMBL5223988 | 0.80 | F10 (0.89) | F10 | |
| SCHEMBL5222608 | 0.80 | F10 (1.00) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1444201-A1 | 2-(3-SULFONYLAMINO-2-OXOPYRROLIDIN-1-YL)PROPANAMIDES AS FACTOR XA INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-08-11 | — | — | EP | disclosed |
| WO-2003043981-A1 | 2-(3-SULFONYLAMINO-2-OXOPYRROLIDIN-1-YL)PROPANAMIDES AS FACTOR XA INHIBITORS | GLAXO GROUP LIMITED (GB) | 2003-05-30 | — | — | WO | disclosed |