Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4906458 | 0.97 | KMT2A (0.54) | KMT2ATLR2TLR1MDM2EPHX2 | |
| SCHEMBL28629484 | 0.89 | KMT2A (0.58) | KMT2ATLR2TLR1MDM2EPHX2 | |
| SCHEMBL28629485 | 0.89 | KMT2A (0.58) | KMT2ATLR2TLR1MDM2EPHX2 | |
| SCHEMBL31758332 | 0.89 | KMT2A (0.58) | KMT2ATLR2TLR1MDM2EPHX2 | |
| Hydrochloric Acid SCHEMBL29380070 | 0.88 | KMT2A (0.57) | KMT2ATLR2TLR1MDM2EPHX2 | |
| SCHEMBL29482638 | 0.85 | KMT2A (0.61) | KMT2ATLR2MDM2EPHX2CASP3 | |
| SCHEMBL22127844 | 0.85 | KMT2A (0.61) | KMT2ATLR2MDM2EPHX2CASP3 | |
| SCHEMBL22127873 | 0.85 | KMT2A (0.61) | KMT2ATLR2MDM2EPHX2CASP3 | |
| Hydrochloric Acid SCHEMBL29902249 | 0.85 | KMT2A (0.52) | KMT2ATLR2TLR1MDM2EPHX2 | |
| SCHEMBL22127898 | 0.83 | KMT2A (0.57) | KMT2ATLR2EPHX2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458378-A1 | AMINO ACID DERIVATIVES USEFUL FOR THE TREATMENT OF ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003045378-A1 | AMINO ACID DERIVATIVES USEFUL FOR THE TREATMENT OF ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2003-06-05 | — | — | WO | disclosed |