Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4348909 | 0.98 | MAPT (0.45) | MAPTMEN1KMT2APLA2G1BATG4B | |
| SCHEMBL6247704 | 0.97 | MAPT (0.41) | MAPTMEN1KMT2APLA2G1BATG4B | |
| SCHEMBL6670236 | 0.93 | MAPT (0.38) | MAPTMEN1KMT2APLA2G1BATG4B | |
| SCHEMBL4351160 | 0.92 | SLC6A4 (0.43) | MEN1KMT2AGAALMNAALDH1A1 | |
| SCHEMBL4350918 | 0.91 | NPC1 (0.45) | MAPTMEN1KMT2APLA2G1BATG4B | |
| SCHEMBL4349809 | 0.86 | SMN1; SMN2 (0.43) | MAPTMEN1KMT2APKMLMNA | |
| SCHEMBL4342324 | 0.86 | MAPT (0.46) | MAPTMEN1KMT2APLA2G1BATG4B | |
| SCHEMBL4354316 | 0.86 | BLM (0.38) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL4351716 | 0.85 | TBXA2R (0.44) | MAPTMEN1KMT2APLA2G1BATG4B | |
| SCHEMBL4357651 | 0.83 | MAPT (0.43) | MAPTMEN1KMT2APLA2G1BATG4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004030664-A2 | NEW COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF | JERINI AG (DE) | 2004-04-15 | — | — | WO | claimed |