Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.38 |
| ▸ | CTSC | P53634 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6670337 | 1.00 | TUBB1 (0.47) | TUBB1MMP8OPRK1CTSCCTSD | |
| SCHEMBL4924404 | 0.88 | TUBB1 (0.51) | TUBB1MMP8CTSDSMN1; SMN2 | |
| SCHEMBL4924411 | 0.88 | TUBB1 (0.51) | TUBB1MMP8CTSDSMN1; SMN2 | |
| SCHEMBL12201938 | 0.85 | TUBB1 (0.46) | TUBB1SMN1; SMN2 | |
| SCHEMBL4370499 | 0.84 | TUBB1 (0.54) | TUBB1MMP8SMN1; SMN2 | |
| SCHEMBL4370496 | 0.84 | TUBB1 (0.54) | TUBB1MMP8SMN1; SMN2 | |
| SCHEMBL4924628 | 0.84 | TUBB1 (0.54) | TUBB1MMP8SMN1; SMN2 | |
| SCHEMBL4924632 | 0.84 | TUBB1 (0.54) | TUBB1MMP8SMN1; SMN2 | |
| SCHEMBL6683206 | 0.84 | TUBB1 (0.48) | TUBB1MMP8CTSDSMN1; SMN2 | |
| SCHEMBL6671594 | 0.84 | TUBB1 (0.48) | TUBB1MMP8CTSDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026293-A2 | HEMIASTERLIN DERIVATIVES FOR TREATING RESISTANT TUMORS | WYETH HOLDINGS CORPORATION (US) | 2004-04-01 | — | — | WO | disclosed |