Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.46 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14568137 | 0.82 | TUBB1 (0.67) | TUBB1 | |
| SCHEMBL13682076 | 0.82 | TUBB1 (0.67) | TUBB1 | |
| SCHEMBL58750 | 0.82 | TUBB1 (0.67) | TUBB1 | |
| SCHEMBL5980725 | 0.82 | TUBB1 (0.67) | TUBB1 | |
| SCHEMBL57979 | 0.82 | TUBB1 (0.67) | TUBB1 | |
| SCHEMBL57410 | 0.82 | TUBB1 (0.67) | TUBB1 | |
| SCHEMBL58344 | 0.82 | TUBB1 (0.67) | TUBB1 | |
| SCHEMBL14591405 | 0.82 | TUBB1 (0.67) | TUBB1 | |
| SCHEMBL14186137 | 0.82 | TUBB1 (0.67) | TUBB1 | |
| SCHEMBL6799344 | 0.80 | TUBB1 (0.64) | TUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026293-A2 | HEMIASTERLIN DERIVATIVES FOR TREATING RESISTANT TUMORS | WYETH HOLDINGS CORPORATION (US) | 2004-04-01 | — | — | WO | disclosed |