Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 2/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6668479 | 0.88 | SLC1A1 (0.43) | SLC1A1SLC1A3SLC1A2MMP1MMP2 | |
| SCHEMBL10009888 | 0.88 | TSHR (0.37) | SLC1A1SLC1A3SLC1A2TSHRKMT2A | |
| SCHEMBL21427132 | 0.82 | TDP1 (0.42) | SLC1A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL3410284 | 0.81 | TSHR (0.46) | TSHRKMT2AHSD17B10MGAMGAA | |
| SCHEMBL8133020 | 0.79 | CA12 (0.34) | TSHR | |
| SCHEMBL10012560 | 0.78 | TSHR (0.32) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL19035870 | 0.78 | TDP1 (0.42) | TSHRKMT2AHSD17B10MGAMGAA | |
| SCHEMBL11417337 | 0.77 | TDP1 (0.54) | SLC1A1TSHRKMT2AHSD17B10MGAM | |
| SCHEMBL10010544 | 0.77 | TSHR (0.34) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL6043806 | 0.77 | TDP1 (0.50) | SLC1A1SLC1A3SLC1A2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831767-B1 | ALPHA HYDROXYACID ESTERS FOR SKIN AGING | YU RUEY J (US) | 2004-09-22 | — | — | EP | disclosed |
| EP-0831767-A4 | ALPHA HYDROXYACID ESTERS FOR SKIN AGING | YU RUEY J (US) | 2000-05-17 | — | — | EP | disclosed |
| EP-0776884-B1 | SUBSTITUTED AMIDE DERIVATIVE | BANYU PHARMA CO LTD (JP) | 2000-01-05 | — | — | EP | disclosed |
| EP-0831767-A1 | ALPHA HYDROXYACID ESTERS FOR SKIN AGING | Yu, Ruey J., Dr. (US) | 1998-04-01 | — | — | EP | disclosed |
| US-5686489-A | TOPICALLY APPLIED TO INDUCE GLYCOSAMINOGLYCAN, PROTEOGLYCAN, COLLAGEN AND ELASTIN BIOSYNTHESIS; WRINKLE RESISTANCE | TRISTRATA TECHNOLOGY, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| US-5643958-A | ANTITUMOR | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0776884-A1 | SUBSTITUTED AMIDE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |
| WO-1996040047-A1 | ALPHA HYDROXYACID ESTERS FOR SKIN AGING | YU RUEY J (US) | 1996-12-19 | — | — | WO | disclosed |