SCHEMBL6671383

SCHEMBL6671383

CC(O)C(=O)NC(C)(CO)CO

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
PTGS1 P23219 1/20 0.36
KCNH2 Q12809 1/20 0.36
PIK3CD O00329 1/20 0.32
TP53 P04637 1/20 0.32
POLB P06746 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3216320 0.84 KMT2A (0.35) KMT2AMEN1PTGS1KCNH2PIK3CD
SCHEMBL1582839 0.82 MEN1 (0.36) KMT2AMEN1PTGS1KCNH2PIK3CD
SCHEMBL16176158 0.79 MEN1 (0.38) KMT2AMEN1PTGS1KCNH2TP53
SCHEMBL8229637 0.78 POLB (0.46) KMT2AMEN1PIK3CDTP53POLB
SCHEMBL8222052 0.78 POLB (0.46) KMT2AMEN1PIK3CDTP53POLB
SCHEMBL23084588 0.78 POLB (0.46) KMT2AMEN1PIK3CDTP53POLB
SCHEMBL11518500 0.77 MEN1 (0.36) KMT2AMEN1PTGS1KCNH2PIK3CD
SCHEMBL6547109 0.75 PIK3CD (0.32) KMT2APIK3CD
SCHEMBL19512291 0.72 KMT2A (0.39) KMT2APOLB
SCHEMBL25763073 0.72 KMT2A (0.39) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4143159-A SKIN-CARE AGENTS CONTAINING HYDROXYALKYL CARBOXAMIDES AND PROCESS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1979-03-06 US claimed
WO-2004037159-A2 COMPOUNDS, COMPOSITIONS AND METHODS FOR MODULATING FAT METABOLISM OBETHERAPY BIOTECHNOLOGY (FR) 2004-05-06 WO disclosed