Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.51 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7606712 | 0.94 | PTGER4 (0.55) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6308788 | 0.94 | PTGER4 (0.55) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6556661 | 0.94 | PTGER4 (0.55) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6686656 | 0.88 | PTGER4 (0.60) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6557846 | 0.84 | PTGER4 (0.55) | PTGER4PTGER3PTGER2 | |
| SCHEMBL7606718 | 0.84 | PTGER4 (0.50) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6558651 | 0.83 | PTGER3 (0.61) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6758333 | 0.82 | PTGER4 (0.69) | PTGER4PTGER3PTGER2 | |
| SCHEMBL4988619 | 0.82 | PTGER4 (0.53) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6315788 | 0.82 | PTGER4 (0.69) | PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461026-A2 | METHOD FOR TREATING OCULAR HYPERTENSION | Merck & Co., Inc. (US) | 2004-09-29 | — | — | EP | disclosed |
| WO-2003047513-A2 | METHOD FOR TREATING OCULAR HYPERTENSION | MERCK & CO., INC. (US) | 2003-06-12 | — | — | WO | disclosed |