Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 2/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | FPGS | Q05932 | 6/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 3/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.41 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27566287 | 0.95 | CXCR4 (0.53) | CXCR4FOLH1NPC1LMNAPOLB | |
| SCHEMBL6018116 | 0.95 | CXCR4 (0.53) | CXCR4FOLH1NPC1LMNAPOLB | |
| Phenylhydrazine SCHEMBL6690774 | 0.91 | CXCR4 (0.50) | CXCR4FOLH1NPC1LMNAPOLB | |
| SCHEMBL27568576 | 0.90 | CXCR4 (0.47) | CXCR4FOLH1KMT2AITGB3ITGA2B | |
| SCHEMBL6667469 | 0.90 | CXCR4 (0.47) | CXCR4FOLH1KMT2AITGB3ITGA2B | |
| SCHEMBL6018220 | 0.90 | CXCR4 (0.51) | CXCR4FOLH1NPC1LMNAPOLB | |
| SCHEMBL6670076 | 0.90 | CXCR4 (0.48) | CXCR4FOLH1NPC1LMNAPOLB | |
| SCHEMBL27616554 | 0.89 | CXCR4 (0.54) | CXCR4NPC1LMNAPOLBRAB9A | |
| SCHEMBL6018126 | 0.89 | CXCR4 (0.54) | CXCR4NPC1LMNAPOLBRAB9A | |
| SCHEMBL6018262 | 0.87 | CXCR4 (0.57) | CXCR4FOLH1NPC1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157818-A1 | Cxcr4-antagonistic drugs composed of nitrogen-containing compound | KUREHA CORPORATION (JP) | 2004-08-12 | — | — | US | disclosed |
| EP-1389460-A1 | CXCR4-ANTAGONISTIC DRUGS COMPRISING NITROGEN-CONTAINING COMPOUND | Kureha Chemical Industry Co., Ltd. (JP) | 2004-02-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157818-A1 | Cxcr4-antagonistic drugs composed of nitrogen-containing compound | CXCR4, CXCR1, CXCR2 | CXCR4 1/4885FOLH1 2694/4885NPC1 943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.