Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 17/20 | 0.52 |
| ▸ | LPAR5 | Q9H1C0 | 15/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3690872 | 0.88 | LPAR1 (0.46) | LPAR1LPAR5ACHE | |
| SCHEMBL3690100 | 0.76 | LPAR1 (0.48) | LPAR1LPAR5ACHELPAR3 | |
| SCHEMBL5739117 | 0.76 | LPAR1 (0.59) | LPAR1LPAR5ACHE | |
| SCHEMBL3696304 | 0.75 | LPAR1 (0.50) | LPAR1LPAR5LPAR3 | |
| SCHEMBL6540096 | 0.74 | LPAR1 (0.54) | LPAR1LPAR5 | |
| SCHEMBL6540580 | 0.74 | LPAR1 (0.52) | LPAR1LPAR5 | |
| SCHEMBL6541221 | 0.73 | LPAR1 (0.52) | LPAR1LPAR5 | |
| SCHEMBL11947088 | 0.73 | LPAR1 (0.44) | LPAR1LPAR5 | |
| SCHEMBL14026227 | 0.72 | LPAR1 (0.49) | LPAR1LPAR5LPAR3 | |
| SCHEMBL7228409 | 0.72 | MEN1 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026305-A9 | DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONIST | LILLY CO ELI (US) | 2004-05-13 | — | — | WO | disclosed |