Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 18/20 | 0.92 |
| ▸ | HRH1 | P35367 | 3/20 | 0.92 |
| ▸ | MAOA | P21397 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.60 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6071401 | 0.96 | HRH3 (1.00) | HRH3HRH1SLC2A1 | |
| SCHEMBL14287596 | 0.92 | HRH3 (0.93) | HRH3HRH1MAOAMAOB | |
| SCHEMBL6675509 | 0.92 | HRH3 (1.00) | HRH3HRH1 | |
| Hydrochloric Acid SCHEMBL5093983 | 0.91 | HRH3 (0.91) | HRH3HRH1MAOAMAOB | |
| SCHEMBL14287568 | 0.88 | HRH3 (1.00) | HRH3HRH1 | |
| SCHEMBL14287578 | 0.88 | HRH3 (1.00) | HRH3HRH1 | |
| Hydrochloric Acid SCHEMBL5093952 | 0.87 | HRH3 (0.97) | HRH3HRH1SLC2A1 | |
| Hydrochloric Acid SCHEMBL5101240 | 0.87 | HRH3 (0.97) | HRH3HRH1SLC2A1 | |
| SCHEMBL491851 | 0.86 | HRH3 (0.69) | HRH3HRH1MAOAMAOB | |
| SCHEMBL14287582 | 0.84 | HRH3 (0.88) | HRH3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004035544-A1 | BENZO[D]AZEPINE DERIVATIVES FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | GLAXO GROUP LIMITED (GB) | 2004-04-29 | — | — | WO | disclosed |