Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.36 |
| ▸ | GPR142 | Q7Z601 | 5/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5207691 | 0.74 | DPP4 (0.49) | DPP4DPP8DPP9GPR142CAPN1 | |
| SCHEMBL7401594 | 0.74 | DPP4 (0.49) | DPP4DPP8DPP9GPR142CAPN1 | |
| SCHEMBL7337840 | 0.74 | CAPN1 (0.41) | DPP4DPP8DPP9GPR142CAPN1 | |
| SCHEMBL5795615 | 0.73 | DPP4 (0.40) | DPP4DPP8DPP9GPR142CAPN1 | |
| SCHEMBL7275102 | 0.73 | KDM4E (0.40) | DPP4DPP8DPP9GPR142CAPN1 | |
| SCHEMBL9565308 | 0.72 | KDM4E (0.44) | DPP4DPP8DPP9GPR142CAPN1 | |
| SCHEMBL21216051 | 0.72 | PPARG (0.40) | DPP4DPP8DPP9GPR142CAPN1 | |
| SCHEMBL990478 | 0.71 | DPP4 (0.49) | DPP4DPP8DPP9GPR142PKM | |
| SCHEMBL5907044 | 0.71 | DPP4 (0.49) | DPP4DPP8DPP9GPR142PKM | |
| SCHEMBL9079440 | 0.71 | DPP4 (0.38) | DPP4DPP8DPP9GPR142CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1069118-B1 | PROCESS FOR PRODUCING 4-THIAZOLYLMETHYL DERIVATIVE | SHIONOGI & CO (JP) | 2004-09-22 | — | — | EP | disclosed |
| US-6506903-B1 | By reacting 4-methylthiazole with N-halosuccinimide in solvent in presence of 2,2-azobisisobutyronitrile; halogenation, catalysis | SHIONOGI & CO., LTD. (JP) | 2003-01-14 | — | — | US | disclosed |
| EP-1069118-A1 | PROCESS FOR PRODUCING 4-THIAZOLYLMETHYL DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2001-01-17 | — | — | EP | disclosed |