Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4348741 | 0.91 | EPHX1 (0.56) | EPHX1EPHX2NPC1RAB9APOLB | |
| SCHEMBL4347164 | 0.82 | KMT2A (0.53) | NPC1RAB9APOLBMAPTALDH1A1 | |
| SCHEMBL4356013 | 0.78 | EPHX1 (0.51) | EPHX1EPHX2NPC1RAB9APOLB | |
| SCHEMBL4353768 | 0.77 | SMN1; SMN2 (0.49) | EPHX1EPHX2NPC1RAB9AMAPT | |
| SCHEMBL4348759 | 0.76 | EPHX1 (0.50) | EPHX1EPHX2NPC1RAB9APOLB | |
| SCHEMBL6672086 | 0.75 | EPHX1 (0.36) | EPHX1EPHX2KCNH2NPC1RAB9A | |
| SCHEMBL4345960 | 0.75 | EPHX1 (0.64) | EPHX1EPHX2NPC1RAB9APOLB | |
| SCHEMBL4351271 | 0.74 | EPHX1 (0.60) | EPHX1EPHX2NPC1RAB9APOLB | |
| SCHEMBL4345381 | 0.74 | EPHX1 (0.63) | EPHX1EPHX2NPC1RAB9APOLB | |
| SCHEMBL6566791 | 0.74 | POLB (0.46) | EPHX2NPC1RAB9APOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004030664-A2 | NEW COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF | JERINI AG (DE) | 2004-04-15 | — | — | WO | claimed |