SCHEMBL6672229 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	TSHR	P16473	1/20	0.70

▸	CA1	P00915	6/20	0.64

▸	CA2	P00918	6/20	0.64

▸	NPC1	O15118	1/20	0.64

▸	RAB9A	P51151	1/20	0.64

▸	GRK6	P43250	2/20	0.54

▸	SLC5A2	P31639	2/20	0.48

▸	PYGB	P11216	2/20	0.45

▸	GAA	P10253	1/20	0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30003604	1.00	TSHR (0.70)	TSHRCA1CA2NPC1RAB9A
SCHEMBL13995569	0.86	TSHR (0.55)	TSHRCA1CA2NPC1RAB9A
SCHEMBL13995568	0.86	TSHR (0.55)	TSHRCA1CA2NPC1RAB9A
SCHEMBL13680075	0.84	CA1 (0.68)	TSHRCA1CA2NPC1RAB9A
SCHEMBL6686920	0.84	TSHR (0.66)	TSHRCA1CA2NPC1RAB9A
SCHEMBL6675392	0.84	TSHR (0.66)	TSHRCA1CA2NPC1RAB9A
SCHEMBL2573470	0.84	NPC1 (0.76)	TSHRCA1CA2NPC1RAB9A
SCHEMBL14353200	0.84	NPC1 (0.76)	TSHRCA1CA2NPC1RAB9A
SCHEMBL2573474	0.84	NPC1 (0.76)	TSHRCA1CA2NPC1RAB9A
SCHEMBL14478652	0.84	NPC1 (0.76)	TSHRCA1CA2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2004037159-A2	COMPOUNDS, COMPOSITIONS AND METHODS FOR MODULATING FAT METABOLISM	OBETHERAPY BIOTECHNOLOGY (FR)	2004-05-06	—	—	WO	disclosed