Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.49 |
| ▸ | Q9HBH1 | 4/20 | 0.34 | |
| ▸ | MMP2 | P08253 | 5/20 | 0.30 |
| ▸ | MMP3 | P08254 | 5/20 | 0.30 |
| ▸ | MMP1 | P03956 | 3/20 | 0.30 |
| ▸ | MMP7 | P09237 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6672632 | 1.00 | TUBB1 (0.49) | TUBB1PDFMMP2MMP3MMP1 | |
| SCHEMBL6672636 | 1.00 | TUBB1 (0.49) | TUBB1PDFMMP2MMP3MMP1 | |
| SCHEMBL6806519 | 1.00 | TUBB1 (0.49) | TUBB1PDFMMP2MMP3MMP1 | |
| SCHEMBL6675943 | 0.89 | TUBB1 (0.61) | TUBB1PDFMMP2MMP3MMP1 | |
| SCHEMBL6670942 | 0.89 | TUBB1 (0.61) | TUBB1PDFMMP2MMP3MMP1 | |
| SCHEMBL6675933 | 0.89 | TUBB1 (0.61) | TUBB1PDFMMP2MMP3MMP1 | |
| SCHEMBL6670957 | 0.89 | TUBB1 (0.61) | TUBB1PDFMMP2MMP3MMP1 | |
| SCHEMBL4369874 | 0.86 | TUBB1 (0.53) | TUBB1PDF | |
| SCHEMBL15434849 | 0.84 | TUBB1 (0.50) | TUBB1PDF | |
| SCHEMBL88602 | 0.84 | TUBB1 (0.47) | TUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026293-A2 | HEMIASTERLIN DERIVATIVES FOR TREATING RESISTANT TUMORS | WYETH HOLDINGS CORPORATION (US) | 2004-04-01 | — | — | WO | disclosed |