SCHEMBL6672797

SCHEMBL6672797

CN1CCC(Oc2cc(NS(=O)(=O)c3cnc(Cl)c(Br)c3)ccc2Cl)C1

nearest known ligand 0.66

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 12/20 0.66
ALDH1A1 P00352 4/20 0.46
LMNA P02545 2/20 0.46
HTT P42858 2/20 0.44
ERBB2 P04626 1/20 0.42
EPHA2 P29317 1/20 0.42
KDR P35968 1/20 0.42
EPHB4 P54760 1/20 0.42
KMT2A Q03164 1/20 0.42
POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5743996 1.00 UTS2R (0.66) UTS2RALDH1A1LMNAHTTERBB2
SCHEMBL5744078 0.92 UTS2R (0.55) UTS2RALDH1A1LMNAHTTERBB2
SCHEMBL6821210 0.89 UTS2R (0.65) UTS2RALDH1A1LMNA
SCHEMBL5741925 0.89 UTS2R (0.65) UTS2RALDH1A1LMNA
SCHEMBL5834807 0.87 UTS2R (0.70) UTS2RLMNAERBB2EPHA2KDR
SCHEMBL5834811 0.87 UTS2R (0.70) UTS2RLMNAERBB2EPHA2KDR
SCHEMBL6679727 0.86 UTS2R (0.58) UTS2RALDH1A1LMNAERBB2EPHA2
SCHEMBL6674000 0.86 UTS2R (0.58) UTS2RERBB2EPHA2KDREPHB4
SCHEMBL6679730 0.86 UTS2R (0.58) UTS2RALDH1A1LMNAERBB2EPHA2
SCHEMBL6674005 0.86 UTS2R (0.58) UTS2RERBB2EPHA2KDREPHB4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004043463-A2 SULFONAMIDES SMITHKLINE BEECHAM CORPORATION (US) 2004-05-27 WO disclosed