Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 10/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7093694 | 0.85 | KCNH2 (0.39) | KCNH2SCN5A | |
| SCHEMBL7097223 | 0.84 | KCNH2 (0.37) | KCNH2SCN5AKDM4EMEN1ALDH1A1 | |
| SCHEMBL7094265 | 0.84 | KCNH2 (0.38) | KCNH2SCN5AKDM4EMEN1ALDH1A1 | |
| SCHEMBL6670336 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL6670759 | 0.82 | KCNH2 (0.37) | KCNH2SCN5AKDM4EMEN1ALDH1A1 | |
| SCHEMBL6671956 | 0.81 | KCNH2 (0.44) | KCNH2SCN5A | |
| SCHEMBL7093428 | 0.81 | KCNH2 (0.40) | KCNH2SCN5A | |
| SCHEMBL6670468 | 0.81 | — | — | |
| SCHEMBL6704929 | 0.80 | CACNA1F (0.34) | KCNH2 | |
| SCHEMBL6671615 | 0.80 | KCNH2 (0.38) | KCNH2SCN5AKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401830-A2 | QUINAZOLINEDIONES AS ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2004-03-31 | — | — | EP | claimed |
| WO-2002102793-A2 | QUINAZOLINEDIONES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2002-12-27 | — | — | WO | claimed |