Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 1/20 | 0.69 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL285416 | 0.98 | POLB (0.72) | POLBSMN1; SMN2NPC1RAB9AHDAC3 | |
| SCHEMBL28802070 | 0.86 | SMN1; SMN2 (0.56) | POLBSMN1; SMN2NPC1RAB9AHDAC3 | |
| SCHEMBL3606677 | 0.84 | NPC1 (0.96) | POLBSMN1; SMN2NPC1RAB9ABCHE | |
| SCHEMBL3592351 | 0.84 | NPC1 (0.96) | POLBSMN1; SMN2NPC1RAB9ABCHE | |
| SCHEMBL3598215 | 0.84 | NPC1 (0.96) | POLBSMN1; SMN2NPC1RAB9ABCHE | |
| SCHEMBL3603641 | 0.84 | NPC1 (0.96) | POLBSMN1; SMN2NPC1RAB9ABCHE | |
| SCHEMBL3600997 | 0.84 | NPC1 (0.96) | POLBSMN1; SMN2NPC1RAB9ABCHE | |
| SCHEMBL4890046 | 0.84 | NPC1 (0.96) | POLBSMN1; SMN2NPC1RAB9ABCHE | |
| Bromide SCHEMBL4887911 | 0.82 | NPC1 (1.00) | POLBSMN1; SMN2NPC1RAB9ABCHE | |
| Bromide SCHEMBL3595600 | 0.82 | NPC1 (1.00) | POLBSMN1; SMN2NPC1RAB9ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318177-B1 | Compound, in particular marker-dye, based on polymethines | DYOMICS GMBH (DE) | 2004-09-22 | — | — | EP | disclosed |
| EP-1318177-A2 | Compound, in particular marker-dye, based on polymethines | Dyomics GmbH (DE) | 2003-06-11 | — | — | EP | disclosed |