Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 8/20 | 0.61 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24845654 | 0.82 | PRCP (0.71) | PRCPSLC22A1TSHRNPSR1GAA | |
| SCHEMBL28763199 | 0.81 | PRCP (0.61) | PRCPSLC22A1TSHRNPSR1GAA | |
| SCHEMBL31569038 | 0.79 | PRCP (0.77) | PRCPSLC22A1TSHRNPSR1GAA | |
| SCHEMBL31158625 | 0.76 | PRCP (1.00) | PRCPSLC22A1TSHRNPSR1GAA | |
| SCHEMBL1012767 | 0.76 | PRCP (1.00) | PRCPSLC22A1TSHRNPSR1GAA | |
| SCHEMBL24091985 | 0.76 | PRCP (1.00) | PRCPSLC22A1TSHRNPSR1GAA | |
| SCHEMBL29768316 | 0.76 | PRCP (1.00) | PRCPSLC22A1TSHRNPSR1GAA | |
| SCHEMBL5102163 | 0.76 | PRCP (0.63) | PRCPSLC22A1TSHRNPSR1GAA | |
| SCHEMBL28209057 | 0.72 | PRCP (0.71) | PRCPSLC22A1TSHRNPSR1GAA | |
| SCHEMBL4144168 | 0.72 | PRCP (0.71) | PRCPSLC22A1TSHRNPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149079-B1 | TETRAHYDRO ISOQUINO LINEALKANOL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SK CORP (KR) | 2004-04-21 | — | — | EP | disclosed |
| CN-1142913-C | Tetrahydroisoquinolinealkanol derivatives and pharmaceutical compositions contg. same | SK��ʽ���� | 2004-03-24 | — | — | CN | disclosed |
| CN-1334804-A | Tetrahydroisoquinolinealkanol derivatives and pharmaceutical compositions contg. same | SK CORP (KR) | 2002-02-06 | — | — | CN | disclosed |
| EP-1149079-A1 | TETRAHYDRO ISOQUINO LINEALKANOL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SK Corporation (KR) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000046204-A1 | TETRAHYDRO ISOQUINO LINEALKANOL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SK CORPORATION (KR) | 2000-08-10 | — | — | WO | disclosed |
| US-5955471-A | USEFUL IN THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS, INCLUDING DEPRESSION | SK CORPORATION (US) | 1999-09-21 | — | — | US | disclosed |