Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.56 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28763197 | 0.86 | PRCP (0.58) | PRCPSLC22A1OPRM1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6065276 | 0.81 | PRCP (0.59) | PRCPSLC22A1OPRM1SMN1; SMN2ALDH1A1 | |
| SCHEMBL30167262 | 0.81 | PRCP (0.59) | PRCPSLC22A1OPRM1SMN1; SMN2ALDH1A1 | |
| SCHEMBL16308969 | 0.78 | PRCP (0.65) | PRCPSLC22A1OPRM1SMN1; SMN2ALDH1A1 | |
| SCHEMBL31569387 | 0.78 | PRCP (0.65) | PRCPSLC22A1OPRM1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3798032 | 0.78 | PRCP (0.65) | PRCPSLC22A1OPRM1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4049149 | 0.78 | PRCP (0.65) | PRCPSLC22A1OPRM1SMN1; SMN2ALDH1A1 | |
| SCHEMBL13977536 | 0.76 | PRCP (0.67) | PRCPSLC22A1OPRM1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5898800 | 0.76 | PRCP (0.61) | PRCPSLC22A1OPRM1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8719925 | 0.75 | PRCP (0.65) | PRCPSLC22A1OPRM1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149079-B1 | TETRAHYDRO ISOQUINO LINEALKANOL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SK CORP (KR) | 2004-04-21 | — | — | EP | disclosed |
| CN-1142913-C | Tetrahydroisoquinolinealkanol derivatives and pharmaceutical compositions contg. same | SK��ʽ���� | 2004-03-24 | — | — | CN | disclosed |
| CN-1334804-A | Tetrahydroisoquinolinealkanol derivatives and pharmaceutical compositions contg. same | SK CORP (KR) | 2002-02-06 | — | — | CN | disclosed |
| EP-1149079-A1 | TETRAHYDRO ISOQUINO LINEALKANOL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SK Corporation (KR) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000046204-A1 | TETRAHYDRO ISOQUINO LINEALKANOL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SK CORPORATION (KR) | 2000-08-10 | — | — | WO | disclosed |
| US-5955471-A | USEFUL IN THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS, INCLUDING DEPRESSION | SK CORPORATION (US) | 1999-09-21 | — | — | US | disclosed |