SCHEMBL6673573

SCHEMBL6673573

CN(C)CC1=C(c2ccccc2C([O])c2ccccc2)CC=C1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 3/20 0.36
HRH1 P35367 3/20 0.36
TDP1 Q9NUW8 1/20 0.35
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
CHRM5 P08912 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRM3 P20309 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3215189 0.81 HTR2A (0.35) HTR2AHRH1TDP1TSHRCHRM2
SCHEMBL3207529 0.80 SLC6A4 (0.32) HRH1ALDH1A1TSHRCHRM2CHRM4
SCHEMBL3212839 0.77 TDP1 (0.36) TDP1ALDH1A1TSHRALOX15
Hydrochloric Acid SCHEMBL3194421 0.75 CHRM2 (0.30) HRH1CHRM2CHRM4CHRM5CHRM1
Hydrochloric Acid SCHEMBL3194427 0.75
Hydrochloric Acid SCHEMBL3262362 0.75
SCHEMBL3214007 0.74 CACNA1F (0.33) HRH1CHRM2CHRM1CHRM3
Hydrochloric Acid SCHEMBL3262364 0.73
Hydrochloric Acid SCHEMBL3262086 0.73
SCHEMBL3214426 0.72 SLC6A4 (0.38) ALDH1A1TSHRCHRM2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1426379-A1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2004-06-09 EP disclosed