Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 2/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.34 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GRM6 | O15303 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL626564 | 0.83 | MAPT (0.51) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL159009 | 0.81 | MAPT (0.53) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL30456072 | 0.80 | MAPT (0.51) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| Water SCHEMBL30261034 | 0.80 | MAPT (0.51) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL29597249 | 0.65 | MAPT (0.46) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL157744 | 0.64 | CYP3A4 (0.45) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL30389963 | 0.62 | CYP3A4 (0.43) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL17347340 | 0.57 | TSHR (0.38) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL31598698 | 0.55 | MAPT (0.54) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL1320586 | 0.53 | KDM4E (0.36) | GRIA1GRIA2GRIA3GRIA4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1138332-B1 | Treatment of poriomania | AJINOMOTO KK (JP) | 2004-06-09 | — | — | EP | claimed |