Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19422817 | 0.85 | KDM4E (0.33) | SMN1; SMN2HSD17B10ALDH1A1HTT | |
| SCHEMBL9499958 | 0.85 | KDM4E (0.38) | SMN1; SMN2HSD17B10 | |
| SCHEMBL14472418 | 0.84 | SMN1; SMN2 (0.36) | SMN1; SMN2HSD17B10ALDH1A1HTTL3MBTL1 | |
| Oxalic Acid SCHEMBL9795145 | 0.81 | KDM4E (0.38) | SMN1; SMN2HSD17B10RIPK1 | |
| SCHEMBL9497704 | 0.80 | CFTR (0.31) | RIPK1 | |
| SCHEMBL2746180 | 0.80 | SMN1; SMN2 (0.34) | SMN1; SMN2HSD17B10ALDH1A1HTTL3MBTL1 | |
| SCHEMBL9682352 | 0.78 | SMN1; SMN2 (0.39) | SMN1; SMN2HSD17B10ALDH1A1HTTL3MBTL1 | |
| SCHEMBL11256982 | 0.78 | SMN1; SMN2 (0.39) | SMN1; SMN2HSD17B10ALDH1A1HTTL3MBTL1 | |
| SCHEMBL5541678 | 0.77 | SMN1; SMN2 (0.32) | SMN1; SMN2HSD17B10ALDH1A1HTT | |
| SCHEMBL13290400 | 0.76 | KDM4E (0.39) | SMN1; SMN2HSD17B10ALDH1A1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037159-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR MODULATING FAT METABOLISM | OBETHERAPY BIOTECHNOLOGY (FR) | 2004-05-06 | — | — | WO | disclosed |