Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN9 | O14815 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 6/20 | 0.36 |
| ▸ | CA2 | P00918 | 6/20 | 0.36 |
| ▸ | CA12 | O43570 | 5/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
| ▸ | PPM1B | O75688 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12035886 | 0.83 | MAPT (0.41) | MAPTPKMCA1CA2CA12 | |
| SCHEMBL23628794 | 0.83 | MAPT (0.41) | MAPTPKMCA1CA2CA12 | |
| SCHEMBL20670658 | 0.83 | MAPT (0.41) | MAPTPKMCA1CA2CA12 | |
| SCHEMBL23628793 | 0.83 | MAPT (0.41) | MAPTPKMCA1CA2CA12 | |
| Hydrochloric Acid SCHEMBL23628738 | 0.81 | MAPT (0.43) | MAPTPKMCA1CA2CA12 | |
| Hydrochloric Acid SCHEMBL23628742 | 0.81 | MAPT (0.43) | MAPTPKMCA1CA2CA12 | |
| Hydrochloric Acid SCHEMBL23628739 | 0.81 | MAPT (0.43) | MAPTPKMCA1CA2CA12 | |
| SCHEMBL852591 | 0.80 | MAPT (0.46) | MAPTPKMCA1CA2CA12 | |
| SCHEMBL12930960 | 0.80 | MAPT (0.46) | MAPTPKMCA1CA2CA12 | |
| SCHEMBL852590 | 0.80 | MAPT (0.46) | MAPTPKMCA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112253-B1 | BRANCHED ALKYL PYRROLIDINE-3-CARBOXYLIC ACIDS | WARNER LAMBERT CO (US) | 2004-10-20 | — | — | EP | disclosed |
| EP-1112253-A1 | BRANCHED ALKYL PYRROLIDINE-3-CARBOXYLIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2001-07-04 | — | — | EP | disclosed |
| US-6245801-B1 | ANTIEPILEPIC AGENTS; BRAIN DISORDERS; PSYCHOLOGICLA DISORDERS | WARNER-LAMBERT COMPANY | 2001-06-12 | — | — | US | disclosed |
| WO-2000015611-A1 | BRANCHED ALKYL PYRROLIDINE-3-CARBOXYLIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2000-03-23 | — | — | WO | disclosed |