Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 15/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4669718 | 1.00 | DPP4 (0.59) | DPP4TSHRALDH1A1HSD17B10THRB | |
| SCHEMBL4668818 | 0.92 | DPP4 (0.66) | DPP4TSHRALDH1A1HSD17B10THRB | |
| SCHEMBL4669803 | 0.90 | TSHR (0.68) | DPP4TSHRALDH1A1HSD17B10THRB | |
| SCHEMBL4668807 | 0.90 | DPP4 (0.68) | DPP4TSHRALDH1A1HSD17B10THRB | |
| SCHEMBL4668656 | 0.89 | DPP4 (0.58) | DPP4TSHRALDH1A1HSD17B10THRB | |
| SCHEMBL1068145 | 0.88 | TSHR (0.64) | DPP4TSHRALDH1A1HSD17B10THRB | |
| SCHEMBL4668663 | 0.86 | TSHR (0.73) | DPP4TSHRALDH1A1HSD17B10THRB | |
| SCHEMBL4667805 | 0.85 | DPP4 (0.52) | DPP4TSHRALDH1A1HSD17B10THRB | |
| SCHEMBL4669779 | 0.85 | DPP4 (0.58) | DPP4TSHRALDH1A1HSD17B10THRB | |
| SCHEMBL4668748 | 0.84 | DPP4 (0.56) | DPP4TSHRALDH1A1HSD17B10THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004033455-A2 | HEMISUCCINATE SALTS OF HETEROCYCLIC DPP-IV INHIBITORS | NOVO NORDISK A/S (DK) | 2004-04-22 | — | — | WO | disclosed |