Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.32 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6674921 | 1.00 | KDM4E (0.35) | KDM4ETSHRHSD17B10SLC1A2MEN1 | |
| SCHEMBL6674927 | 1.00 | KDM4E (0.35) | KDM4ETSHRHSD17B10SLC1A2MEN1 | |
| SCHEMBL6674943 | 1.00 | KDM4E (0.35) | KDM4ETSHRHSD17B10SLC1A2MEN1 | |
| SCHEMBL6677175 | 1.00 | KDM4E (0.35) | KDM4ETSHRHSD17B10SLC1A2MEN1 | |
| SCHEMBL6679446 | 1.00 | KDM4E (0.35) | KDM4ETSHRHSD17B10SLC1A2MEN1 | |
| SCHEMBL6675543 | 1.00 | KDM4E (0.35) | KDM4ETSHRHSD17B10SLC1A2MEN1 | |
| SCHEMBL26520126 | 0.85 | GBA1 (0.31) | GBA1 | |
| SCHEMBL23658151 | 0.83 | GBA1 (0.30) | GBA1 | |
| SCHEMBL18637047 | 0.83 | GBA1 (0.30) | GBA1 | |
| SCHEMBL1934562 | 0.78 | MEN1 (0.36) | KDM4ETSHRHSD17B10SLC1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112253-B1 | BRANCHED ALKYL PYRROLIDINE-3-CARBOXYLIC ACIDS | WARNER LAMBERT CO (US) | 2004-10-20 | — | — | EP | claimed |
| EP-1112253-A1 | BRANCHED ALKYL PYRROLIDINE-3-CARBOXYLIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2001-07-04 | — | — | EP | claimed |
| US-6245801-B1 | ANTIEPILEPIC AGENTS; BRAIN DISORDERS; PSYCHOLOGICLA DISORDERS | WARNER-LAMBERT COMPANY | 2001-06-12 | — | — | US | claimed |
| WO-2000015611-A1 | BRANCHED ALKYL PYRROLIDINE-3-CARBOXYLIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2000-03-23 | — | — | WO | claimed |
| EP-1112253-B1 | BRANCHED ALKYL PYRROLIDINE-3-CARBOXYLIC ACIDS | WARNER LAMBERT CO (US) | 2004-10-20 | — | — | EP | disclosed |
| EP-1112253-A1 | BRANCHED ALKYL PYRROLIDINE-3-CARBOXYLIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2001-07-04 | — | — | EP | disclosed |
| US-6245801-B1 | ANTIEPILEPIC AGENTS; BRAIN DISORDERS; PSYCHOLOGICLA DISORDERS | WARNER-LAMBERT COMPANY | 2001-06-12 | — | — | US | disclosed |
| WO-2000015611-A1 | BRANCHED ALKYL PYRROLIDINE-3-CARBOXYLIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2000-03-23 | — | — | WO | disclosed |