Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 6/20 | 0.72 |
| ▸ | CA9 | Q16790 | 6/20 | 0.60 |
| ▸ | CA1 | P00915 | 4/20 | 0.60 |
| ▸ | CA2 | P00918 | 4/20 | 0.60 |
| ▸ | CA7 | P43166 | 4/20 | 0.60 |
| ▸ | KDR | P35968 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | BRAF | P15056 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | RAF1 | P04049 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6110136 | 0.84 | MCHR1 (0.79) | MCHR1BRAF | |
| SCHEMBL6678768 | 0.84 | MCHR1 (1.00) | MCHR1ALDH1A1NFKB1KCNH2POLB | |
| SCHEMBL6681114 | 0.84 | MCHR1 (0.71) | MCHR1ALDH1A1NFKB1KCNH2POLB | |
| SCHEMBL19668269 | 0.80 | KDR (0.74) | CA9CA1CA2CA7KDR | |
| SCHEMBL6107273 | 0.78 | MCHR1 (1.00) | MCHR1ALDH1A1NFKB1KCNH2POLB | |
| SCHEMBL6678254 | 0.78 | MCHR1 (0.75) | MCHR1ALDH1A1NFKB1KCNH2POLB | |
| SCHEMBL8507800 | 0.77 | MCHR1 (0.73) | MCHR1ALDH1A1NFKB1KCNH2POLB | |
| SCHEMBL118026 | 0.76 | KDR (1.00) | CA9CA1CA2CA7KDR | |
| SCHEMBL29364392 | 0.76 | KDR (1.00) | CA9CA1CA2CA7KDR | |
| SCHEMBL12310641 | 0.76 | KDR (0.76) | CA9CA1CA2CA7KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048319-A1 | NOVEL BENZAMIDE COMPOUNDS FOR USE IN MCH RECEPTOR RELATED DISORDERS | 7TM PHARMA A/S (DK) | 2004-06-10 | — | — | WO | disclosed |