Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6680556 | 0.99 | TAAR1 (0.43) | TAAR1HTTADRA1AHTR2AHTR2C | |
| SCHEMBL6682225 | 0.90 | TAAR1 (0.49) | TAAR1HTTADRA1A | |
| SCHEMBL6676752 | 0.82 | TAAR1 (0.35) | TAAR1 | |
| SCHEMBL6679989 | 0.81 | HTT (0.39) | TAAR1HTT | |
| SCHEMBL6680855 | 0.81 | HTT (0.45) | HTT | |
| Hydrochloric Acid SCHEMBL6676283 | 0.81 | TAAR1 (0.34) | TAAR1 | |
| Hydrochloric Acid SCHEMBL6676152 | 0.80 | HTT (0.44) | HTT | |
| Hydrochloric Acid SCHEMBL6681248 | 0.80 | HTT (0.39) | TAAR1HTT | |
| SCHEMBL6675654 | 0.76 | PTGIR (0.49) | TAAR1ADRA1A | |
| Hydrochloric Acid SCHEMBL6680559 | 0.75 | PTGIR (0.48) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |