Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 3/20 | 1.00 |
| ▸ | RAF1 | P04049 | 1/20 | 1.00 |
| ▸ | MAPK14 | Q16539 | 18/20 | 0.83 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.72 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9923556 | 0.91 | MAPK14 (1.00) | MAPK13RAF1MAPK14MAPK11MAPT | |
| SCHEMBL5575739 | 0.89 | MAPK14 (1.00) | MAPK13RAF1MAPK14MAPK11MAPT | |
| SCHEMBL5573489 | 0.89 | RAF1 (0.80) | MAPK13RAF1MAPK14MAPK11ERBB2 | |
| SCHEMBL939485 | 0.86 | MAPK14 (1.00) | MAPK13RAF1MAPK14MAPK11ERBB2 | |
| SCHEMBL2508762 | 0.85 | MAPK14 (0.80) | MAPK13RAF1MAPK14MAPK11ERBB2 | |
| SCHEMBL16870246 | 0.85 | MAPK14 (0.78) | MAPK13RAF1MAPK14 | |
| SCHEMBL16870189 | 0.85 | MAPK13 (1.00) | MAPK13RAF1MAPK14MAPK11MAPK12 | |
| SCHEMBL28933401 | 0.85 | MAPK13 (0.85) | MAPK13RAF1MAPK14MAPK11MAPK12 | |
| SCHEMBL16870206 | 0.84 | MAPK13 (0.87) | MAPK13RAF1MAPK14MAPK11MAPK12 | |
| SCHEMBL667387 | 0.84 | MAPK14 (1.00) | MAPK13RAF1MAPK14MAPK11ERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250367183-A1 | SUBSTANCE FOR PROMOTING REGENERATION AND REPAIR OF ORGANS OF MAMMALS AND USE THEREOF | INSTITUTE OF ZOOLOGY, CHINESE ACADEMY OF SCIENCES (CN) | 2025-12-04 | — | — | US | claimed |
| EP-4412621-A2 | COMPOSITIONS AND METHODS FOR ENHANCED PROTEIN PRODUCTION | HDT Bio Corp. (US) | 2024-08-14 | — | — | EP | claimed |
| WO-2023241717-A1 | SUBSTANCE FOR PROMOTING REGENERATION AND REPAIR OF ORGANS OF MAMMALS AND USE THEREOF | 中国科学院动物研究所 | 2023-12-21 | — | — | WO | claimed |
| WO-2023056202-A2 | COMPOSITIONS AND METHODS FOR ENHANCED PROTEIN PRODUCTION | HDT BIO CORP. (US) | 2023-04-06 | — | — | WO | claimed |
| US-20120149706-A1 | INHIBITION OF P38 KINASE ACTIVITY USING SUBSTITUTED HETEROCYCLIC UREAS | DUMAS JACQUES (US) | 2012-06-14 | — | — | US | claimed |
| US-20120046290-A1 | INHIBITION OF P38 KINASE ACTIVITY USING SUBSTITUTED HETEROCYCLIC UREAS | BAYER HEALTHCARE LLC | 2012-02-23 | — | — | US | claimed |
| EP-1041982-B1 | INHIBITION OF p38 KINASE ACTIVITY USING SUBSTITUTED HETEROCYCLIC UREAS | BAYER HEALTHCARE LLC (US) | 2011-10-19 | — | — | EP | claimed |
| EP-2324825-A1 | Aryl ureas with angiogenesis inhibiting activity | Bayer Healthcare LLC (US) | 2011-05-25 | — | — | EP | claimed |
| US-7838541-B2 | Aryl ureas with angiogenesis inhibiting activity | BAYER HEALTHCARE, LLC (US) | 2010-11-23 | — | — | US | claimed |
| JP-4403482-B2 | — | — | 2010-01-27 | — | — | JP | claimed |
| US-20070244120-A1 | INHIBITION OF RAF KINASE USING SUBSTITUTED HETEROCYCLIC UREAS | BAYER HEALTHCARE LLC | 2007-10-18 | — | — | US | claimed |
| EP-1041982-A4 | INHIBITION OF p38 KINASE ACTIVITY USING SUBSTITUTED HETEROCYCLIC UREAS | BAYER PHARMACEUTICALS CORP (US) | 2006-06-14 | — | — | EP | claimed |
| EP-1047418-B1 | INHIBITION OF RAF KINASE USING SUBSTITUTED HETEROCYCLIC UREAS | BAYER PHARMACEUTICALS CORP (US) | 2005-07-27 | — | — | EP | claimed |
| CN-1544420-A | Inhibition of raf kinase using substituted heterocyclic ureas | — | 2004-11-10 | — | — | CN | claimed |
| JP-2001526223-A | — | — | 2001-12-18 | — | — | JP | claimed |
| EP-1041982-A1 | INHIBITION OF p38 KINASE ACTIVITY USING SUBSTITUTED HETEROCYCLIC UREAS | Bayer Corporation (US) | 2000-10-11 | — | — | EP | claimed |
| WO-1999032111-A1 | INHIBITION OF p38 KINASE ACTIVITY USING SUBSTITUTED HETEROCYCLIC UREAS | BAYER CORPORATION (US) | 1999-07-01 | — | — | WO | claimed |
| US-20250367183-A1 | SUBSTANCE FOR PROMOTING REGENERATION AND REPAIR OF ORGANS OF MAMMALS AND USE THEREOF | INSTITUTE OF ZOOLOGY, CHINESE ACADEMY OF SCIENCES (CN) | 2025-12-04 | — | — | US | disclosed |
| WO-1999032106-A1 | INHIBITION OF RAF KINASE USING SUBSTITUTED HETEROCYCLIC UREAS | BAYER CORPORATION (US) | 1999-07-01 | — | — | WO | disclosed |
| WO-1999032111-A1 | INHIBITION OF p38 KINASE ACTIVITY USING SUBSTITUTED HETEROCYCLIC UREAS | BAYER CORPORATION (US) | 1999-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149706-A1 | INHIBITION OF P38 KINASE ACTIVITY USING SUBSTITUTED HETEROCYCLIC UREAS | MAPK1, MAP3K1, MAP3K7 | MAPK13 32/4885RAF1 155/4885MAPK14 31/4885 |
| US-20120046290-A1 | INHIBITION OF P38 KINASE ACTIVITY USING SUBSTITUTED HETEROCYCLIC UREAS | MAPK1, MAP3K1, MAP3K7 | MAPK13 32/4885RAF1 155/4885MAPK14 31/4885 |
| US-20070244120-A1 | INHIBITION OF RAF KINASE USING SUBSTITUTED HETEROCYCLIC UREAS | BRAF, RAF1, ARAF | MAPK13 90/4885RAF1 2/4885MAPK14 127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.