Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BID | P55957 | 3/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.43 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.43 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL793234 | 0.98 | PPARA (0.46) | BIDMCL1PPARABCL2L1BAK1 | |
| SCHEMBL27406367 | 0.98 | PPARA (0.46) | BIDMCL1PPARABCL2L1BAK1 | |
| SCHEMBL1052810 | 0.98 | PPARA (0.46) | BIDMCL1PPARABCL2L1BAK1 | |
| SCHEMBL11221193 | 0.98 | PPARA (0.46) | BIDMCL1PPARABCL2L1BAK1 | |
| SCHEMBL27666821 | 0.91 | PPARA (0.48) | BIDMCL1PPARABCL2L1BAK1 | |
| SCHEMBL3639099 | 0.90 | BID (0.54) | BIDMCL1PPARABCL2L1BAK1 | |
| SCHEMBL1217617 | 0.86 | TYR (0.43) | BIDMCL1PPARABCL2L1BAK1 | |
| SCHEMBL14054854 | 0.86 | TYR (0.43) | BIDMCL1PPARABCL2L1BAK1 | |
| SCHEMBL9340012 | 0.86 | DHODH (0.32) | TDP1 | |
| SCHEMBL2206844 | 0.85 | PRKCI (0.40) | MAPTMEN1KMT2ACYP3A4NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453789-A2 | N,N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES | Elan Pharmaceuticals, Inc. (US) | 2004-09-08 | — | — | EP | claimed |
| WO-2003040096-A2 | N, N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES | ELAN PHARMACEUTICALS, INC. (US) | 2003-05-15 | — | — | WO | claimed |