Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 6/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | DGKA | P23743 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27609250 | 0.93 | TSHR (0.59) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL9417606 | 0.93 | TSHR (0.76) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL18100189 | 0.92 | TSHR (0.63) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL402912 | 0.92 | TSHR (0.63) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL2467554 | 0.91 | TSHR (0.72) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL16744245 | 0.89 | TSHR (0.56) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL11654713 | 0.89 | TSHR (0.83) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL209596 | 0.89 | TSHR (0.83) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| 1,6-Hexanediol SCHEMBL1954486 | 0.89 | TSHR (0.83) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL5918785 | 0.89 | TSHR (0.83) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0324569-B1 | Process for preparing functionalized polymeric compositions | ROHM & HAAS (US) | 2004-10-27 | — | — | EP | disclosed |
| US-5130369-A | Polymerization of a monomer with a chain transfer agent and a second monomer with the monomers interacting | ROHM AND HAAS COMPANY (US) | 1992-07-14 | — | — | US | disclosed |
| EP-0324569-A2 | Process for preparing functionalized polymeric compositions | ROHM AND HAAS COMPANY (US) | 1989-07-19 | — | — | EP | disclosed |