Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 6/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15841108 | 0.92 | TSHR (0.55) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL15841030 | 0.87 | TSHR (0.56) | TSHRALDH1A1CYP3A4HPGDHCAR2 | |
| SCHEMBL6680312 | 0.86 | TSHR (0.59) | TSHRALDH1A1CYP3A4HPGDACHE | |
| SCHEMBL14586207 | 0.84 | TSHR (0.50) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL1656561 | 0.83 | TSHR (0.65) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL3177347 | 0.80 | TSHR (0.59) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| 1,4-Butanediol SCHEMBL2467555 | 0.80 | TSHR (0.41) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL1657033 | 0.80 | TSHR (0.48) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL35062 | 0.79 | TSHR (0.83) | TSHRALDH1A1CYP3A4HPGDACHE | |
| SCHEMBL5918785 | 0.79 | TSHR (0.83) | TSHRALDH1A1CYP3A4HPGDACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0324569-B1 | Process for preparing functionalized polymeric compositions | ROHM & HAAS (US) | 2004-10-27 | — | — | EP | disclosed |
| US-5130369-A | Polymerization of a monomer with a chain transfer agent and a second monomer with the monomers interacting | ROHM AND HAAS COMPANY (US) | 1992-07-14 | — | — | US | disclosed |
| EP-0324569-A2 | Process for preparing functionalized polymeric compositions | ROHM AND HAAS COMPANY (US) | 1989-07-19 | — | — | EP | disclosed |