Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 15/20 | 0.53 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.49 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6676293 | 1.00 | ADRB3 (0.53) | ADRB3LPAR1LPAR5ADRB1MEN1 | |
| SCHEMBL6677810 | 0.94 | LPAR1 (0.56) | ADRB3LPAR1LPAR5ADRB1MEN1 | |
| SCHEMBL6677806 | 0.94 | LPAR1 (0.56) | ADRB3LPAR1LPAR5ADRB1MEN1 | |
| SCHEMBL6801224 | 0.91 | ADRB3 (0.43) | ADRB3LPAR1LPAR5ADRB1MEN1 | |
| SCHEMBL6802138 | 0.90 | ADRB3 (0.43) | ADRB3LPAR1LPAR5ADRB1 | |
| SCHEMBL6802133 | 0.90 | ADRB3 (0.43) | ADRB3LPAR1LPAR5ADRB1 | |
| SCHEMBL6678311 | 0.90 | ADRB3 (0.51) | ADRB3LPAR1LPAR5ADRB1MEN1 | |
| SCHEMBL6675747 | 0.89 | LPAR1 (0.42) | ADRB3LPAR1LPAR5ADRB1 | |
| SCHEMBL6675752 | 0.89 | LPAR1 (0.42) | ADRB3LPAR1LPAR5ADRB1 | |
| SCHEMBL6540722 | 0.89 | LPAR1 (0.45) | ADRB3LPAR1LPAR5ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004045610-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2004-06-03 | — | — | WO | disclosed |