Bromide

Bromide

SCHEMBL667642

[Br-].c1ccc([P+](CCC2OCCCO2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.47
CYP2C19 P33261 3/20 0.42
CYP1A2 P05177 2/20 0.42
CYP2D6 P10635 2/20 0.42
ALDH1A1 P00352 1/20 0.42
TSHR P16473 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
SNCA P37840 2/20 0.34
HPGD P15428 3/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
PKM P14618 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
GAA P10253 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8583704 0.97 HIF1A (0.47) HIF1ACYP2C19CYP1A2CYP2D6ALDH1A1
Bromide SCHEMBL1454426 0.93 HIF1A (0.50) HIF1ACYP2C19CYP1A2CYP2D6ALDH1A1
Water SCHEMBL8528246 0.89 HIF1A (0.50) HIF1ACYP2C19CYP1A2CYP2D6ALDH1A1
Bromide SCHEMBL4637900 0.82 HIF1A (0.40) HIF1ACYP2C19CYP1A2CYP2D6ALDH1A1
Iodide SCHEMBL8876694 0.79 HIF1A (0.47) HIF1ACYP2C19CYP1A2CYP2D6ALDH1A1
Bromide SCHEMBL7331525 0.79 HIF1A (0.42) HIF1ACYP2C19CYP1A2CYP2D6ALDH1A1
Bromide SCHEMBL510812 0.74 HIF1A (0.43) HIF1ACYP2C19CYP1A2CYP2D6ALDH1A1
Bromide SCHEMBL1581706 0.73 HIF1A (0.52) HIF1ACYP2C19CYP1A2CYP2D6ALDH1A1
Bromide SCHEMBL11351959 0.71 HIF1A (0.38) HIF1AALDH1A1
Hydrochloric Acid SCHEMBL11598099 0.71 HIF1A (0.41) HIF1ACYP2C19CYP1A2CYP2D6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111943820-A Method for simply and efficiently synthesizing alpha, beta-unsaturated aldehyde without synthesis gas 四川大学 2020-11-17 CN claimed
CN-111825537-A Method for efficiently synthesizing alpha, beta-unsaturated aldehyde without synthesis gas 四川大学 2020-10-27 CN claimed
US-5760809-A INK JET PRINTING XEROX CORPORATION (US) 1998-06-02 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
WO-2026087965-A1 COMPOSITION COMPRISING EPOXY RESIN WITH CONSTRAINED AROMATIC RINGS AND PHOTOBASE 3M INNOVATIVE PROPERTIES COMPANY (US) 2026-04-30 WO disclosed
WO-2025200154-A1 TWO-PART EPOXY COMPOSITION COMPRISING THIOL CURATIVE, AND CATALYST 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-10-02 WO disclosed
WO-2025094828-A1 METHOD FOR PRODUCING HETEROPOLYOXOMETALATE HAVING MODIFIED LACUNARY SITE, OR MIXTURE THEREOF 東京応化工業株式会社 2025-05-08 WO disclosed
EP-3653663-B1 MOLDED ARTICLE AND ITS PRODUCTION METHOD TORAY INDUSTRIES (JP) 2022-12-28 EP disclosed
WO-2022210246-A1 EPOXY RESIN COMPOSITION, CURED EPOXY RESIN PRODUCT, AND COATED FIBER-REINFORCED RESIN MOLDED ARTICLE OBTAINED USING SAME 東レ株式会社 2022-10-06 WO disclosed
CN-113166618-B Adhesive composition and surface protective film DIC株式会社 2022-08-23 CN disclosed
CN-109312232-B Liquid crystal composition, application thereof and liquid crystal display element 捷恩智株式会社 2022-08-16 CN disclosed
CN-109997074-B Method for manufacturing liquid crystal display element without alignment film, and display device 捷恩智株式会社 2022-05-17 CN disclosed
EP-0268148-B1 TETRAHYDRONAPHTHALENE DERIVATIVES AND MEDICAMENTS CONTAINING THEM F. HOFFMANN-LA ROCHE AG (CH) 1991-12-11 EP disclosed
US-5021414-A Antiestrogen IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-06-04 US disclosed
US-4904661-A ANTIESTROGENS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-02-27 US disclosed
US-4808605-A Tetrahydronaphthalene derivatives as calcium antagonists HOFFMANN-LA ROCHE INC. (US) 1989-02-28 US disclosed
EP-0268148-A1 Tetrahydronaphthalene derivatives and medicaments containing them F. HOFFMANN-LA ROCHE AG (CH) 1988-05-25 EP disclosed
US-4732912-A ANTIESTROGENS, ANTITUMOR AGENTS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-03-22 US disclosed
EP-0124369-B1 PHENOL DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-06-24 EP disclosed
EP-0124369-A1 Phenol derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-11-07 EP disclosed