Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.67 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.58 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.58 |
| ▸ | FLT3 | P36888 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6396471 | 1.00 | MEN1 (0.67) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6396469 | 1.00 | MEN1 (0.67) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6389272 | 0.87 | FLT3 (0.61) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6389275 | 0.87 | FLT3 (0.61) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL17927554 | 0.81 | PDGFRB (0.51) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL17927553 | 0.81 | PDGFRB (0.51) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29354248 | 0.81 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5828060 | 0.81 | MEN1 (0.71) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5828518 | 0.81 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5829672 | 0.80 | MEN1 (0.69) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1423393-A1 | CYCLIC INDOLE AND HETEROINDOLE DERIVATIVES, THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | Zentaris GmbH (DE) | 2004-06-02 | — | — | EP | disclosed |
| WO-2003020731-A1 | CYCLIC INDOLE AND HETEROINDOLE DERIVATIVES, THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | ZENTARIS GMBH (DE) | 2003-03-13 | — | — | WO | disclosed |