Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687759 | 0.79 | DPP4 (0.41) | DPP4KCNH2CHRM1 | |
| SCHEMBL6689878 | 0.78 | DPP4 (0.40) | DPP4KCNH2CHRM1CHRM2CHRM3 | |
| SCHEMBL4668591 | 0.70 | DPP4 (0.66) | DPP4KCNH2CHRM1CHRM2CHRM3 | |
| Xanthine SCHEMBL6676645 | 0.69 | DPP4 (0.54) | DPP4KCNH2CHRM1CHRM2CHRM3 | |
| SCHEMBL6573579 | 0.67 | DPP4 (0.39) | DPP4KCNH2CHRM1CHRM2CHRM3 | |
| SCHEMBL5335575 | 0.65 | DPP4 (0.45) | DPP4 | |
| SCHEMBL4669781 | 0.64 | DPP4 (0.41) | DPP4KCNH2 | |
| SCHEMBL4667089 | 0.63 | DPP4 (0.77) | DPP4KCNH2CHRM1CHRM2CHRM3 | |
| SCHEMBL4668920 | 0.63 | DPP4 (0.67) | DPP4KCNH2CHRM1CHRM2CHRM3 | |
| SCHEMBL4667112 | 0.62 | DPP4 (0.75) | DPP4KCNH2CHRM1CHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004033455-A2 | HEMISUCCINATE SALTS OF HETEROCYCLIC DPP-IV INHIBITORS | NOVO NORDISK A/S (DK) | 2004-04-22 | — | — | WO | disclosed |