SCHEMBL667678

SCHEMBL667678

O=[C]C(O)C(O)[C]=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10427686 1.00
SCHEMBL10427707 1.00
SCHEMBL2726510 1.00
SCHEMBL2772175 0.82
SCHEMBL143454 0.82
SCHEMBL2427812 0.76
SCHEMBL10697152 0.76
SCHEMBL1006909 0.74
SCHEMBL720480 0.74
SCHEMBL8708711 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2011508748-A 2011-03-17 JP claimed
JP-2011508747-A 2011-03-17 JP claimed
EP-2250185-A1 NOVEL LUPANE DERIVATIVES Virochem Pharma Inc. (CA) 2010-11-17 EP claimed
EP-2240504-A1 NOVEL C-21-KETO LUPANE DERIVATIVES PREPARATION AND USE THEREOF Virochem Pharma Inc. (CA) 2010-10-20 EP claimed
WO-2009082819-A1 NOVEL LUPANE DERIVATIVES VIROCHEM PHARMA INC. (CA) 2009-07-09 WO claimed
WO-2009082818-A1 NOVEL C-21-KETO LUPANE DERIVATIVES PREPARATION AND USE THEREOF VIROCHEM PHARMA INC. (CA) 2009-07-09 WO claimed
WO-2008057420-A2 EXTENDED TRITERPENE DERIVATIVES PANACOS PHARMACEUTICALS, INC. (US) 2008-05-15 WO claimed
US-20060205697-A1 Novel betulin derivatives, preparation thereof and use thereof MYREXIS, INC. 2006-09-14 US claimed
US-4652672-A BETA BLOCKERS LINDNER WOLFGANG F (AT) 1987-03-24 US claimed
US-20170096446-A1 Extended Triterpene Derivatives MYREXIS, INC. (US) 2017-04-06 US disclosed
US-9505800-B2 Extended triterpene derivatives MYREXIS, INC. (US) 2016-11-29 US disclosed
US-8551956-B2 Compositions containing peptides with non-natural amino acids and methods of use AVON PRODUCTS, INC. (US) 2013-10-08 US disclosed
US-8431556-B2 C-21-keto lupane derivatives preparation and use thereof VERTEX PHARMACEUTICALS INCORPORATED (US) 2013-04-30 US disclosed
US-8269026-B2 Lupane derivatives useful for treating HIV VERTEX PHARMACEUTICALS INCORPORATED (US) 2012-09-18 US disclosed
US-4129586-A Peroxide free radical initiators containing ultraviolet light stabilizing groups PENNWALT CORPORATION (US) 1978-12-12 US disclosed
US-4055714-A POLYMERIZATION CATALYSTS PENNWALT CORPORATION (US) 1977-10-25 US disclosed
US-4045427-A POLYMERIZATION CATALYSTS PENNWALT CORPORATION (US) 1977-08-30 US disclosed
US-4045426-A POLYMERIZATION CATALYSTS PENNWALT CORPORATION (US) 1977-08-30 US disclosed
US-4042773-A REACTION WITH POLYMERS PENNWALT CORPORATION (US) 1977-08-16 US disclosed
US-3956269-A POLYMERIZATION CATALYSTS PENNWALT CORPORATION (US) 1976-05-11 US disclosed