Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 19/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13980535 | 0.91 | KDR (0.76) | KDR | |
| SCHEMBL13980541 | 0.90 | KDR (0.78) | KDR | |
| SCHEMBL4814968 | 0.87 | KDR (0.77) | KDR | |
| SCHEMBL4813427 | 0.85 | KDR (1.00) | KDR | |
| SCHEMBL4815149 | 0.85 | KDR (1.00) | KDR | |
| SCHEMBL4810035 | 0.85 | KDR (0.80) | KDR | |
| SCHEMBL4809489 | 0.85 | KDR (0.80) | KDR | |
| SCHEMBL4804557 | 0.85 | KDR (0.85) | KDR | |
| SCHEMBL4806044 | 0.85 | KDR (1.00) | KDR | |
| SCHEMBL4814948 | 0.84 | KDR (0.84) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472233-A1 | PYRIMIDINE COMPOUNDS | SmithKline Beecham Corporation (US) | 2004-11-03 | — | — | EP | claimed |
| WO-2003066601-A1 | PYRIMIDINE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-08-14 | — | — | WO | claimed |
| EP-1472233-A1 | PYRIMIDINE COMPOUNDS | SmithKline Beecham Corporation (US) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003066601-A1 | PYRIMIDINE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-08-14 | — | — | WO | disclosed |