Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | FABP2 | P12104 | 1/20 | 0.49 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10712634 | 0.82 | TDP1 (0.52) | HPGDMEN1MAPTKMT2ACES2 | |
| SCHEMBL10554594 | 0.81 | PPARA (0.68) | PPARAPPARGFABP2SLC22A12HPGD | |
| SCHEMBL9246353 | 0.81 | CYP2C9 (0.44) | HPGDMEN1MAPTKMT2ACYP2D6 | |
| SCHEMBL11299913 | 0.80 | CES1 (0.46) | MEN1MAPTKMT2ACES2CES1 | |
| SCHEMBL10812552 | 0.80 | HPGD (0.48) | PPARAPPARGFABP2SLC22A12HPGD | |
| SCHEMBL20135443 | 0.80 | CA1 (0.55) | MEN1MAPTKMT2ATSHRCA1 | |
| SCHEMBL18678827 | 0.80 | TPMT (0.45) | CES1CA1CA2GSK3B | |
| SCHEMBL3689915 | 0.80 | HPGD (0.52) | HPGDMAPTKMT2ACES2CES1 | |
| SCHEMBL4983958 | 0.79 | PPARA (0.45) | PPARAPPARGFABP2SLC22A12HPGD | |
| SCHEMBL6199685 | 0.79 | POLB (0.50) | PPARAPPARGFABP2SLC22A12HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046080-A1 | METHOD OF PREPARATION OF DERIVATIVES OF SUBSTITUTED 2-ARYL AIKANOIC ACIDS | ZENTIVA, A.S. (SK) | 2004-06-03 | — | — | WO | disclosed |