Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.37 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.37 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5398394 | 0.91 | MEN1 (0.52) | MEN1KMT2ADPP4HPGDADORA2B | |
| SCHEMBL5418106 | 0.89 | MAPT (0.47) | MEN1KMT2ADPP4HPGDADORA2B | |
| SCHEMBL5398717 | 0.89 | MEN1 (0.45) | MEN1KMT2ADPP4MAPT | |
| SCHEMBL5415311 | 0.87 | KMT2A (0.43) | MEN1KMT2ADPP4HPGDADORA2B | |
| SCHEMBL5411110 | 0.87 | MEN1 (0.47) | MEN1KMT2ADPP4HPGDADORA2B | |
| SCHEMBL5410909 | 0.87 | MEN1 (0.47) | MEN1KMT2ADPP4 | |
| SCHEMBL5405482 | 0.87 | MEN1 (0.44) | MEN1KMT2ADPP4SLC16A3SLC16A1 | |
| SCHEMBL5402322 | 0.86 | MEN1 (0.45) | MEN1KMT2A | |
| SCHEMBL5407553 | 0.86 | MEN1 (0.41) | MEN1KMT2AADORA2BMAPT | |
| SCHEMBL5404381 | 0.86 | MEN1 (0.42) | MEN1KMT2ASLC16A1HPGDADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412355-A1 | NEW PYRAZOLO(3,4-D)PYRIMIDINES INHIBITING H. PYLORI INFECTIONS | AstraZeneca AB (SE) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003002567-A1 | NEW PYRAZOLO[3,4-D]PYRIMIDINES INHIBITING H. PYLORI INFECTIONS | ASTRAZENECA AB (SE) | 2003-01-09 | — | — | WO | disclosed |