Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 17/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 13/20 | 0.43 |
| ▸ | BACE1 | P56817 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6804154 | 0.89 | ADRB3 (0.52) | ADRB3ADRB1 | |
| SCHEMBL6677354 | 0.88 | ADRB3 (0.50) | ADRB3ADRB1 | |
| SCHEMBL6541176 | 0.86 | ADRB3 (0.46) | ADRB3ADRB1BACE1 | |
| SCHEMBL6541170 | 0.86 | ADRB3 (0.46) | ADRB3ADRB1BACE1 | |
| SCHEMBL6804845 | 0.85 | ADRB3 (0.45) | ADRB3ADRB1BACE1 | |
| SCHEMBL6803535 | 0.85 | BACE1 (0.39) | ADRB3ADRB1BACE1 | |
| SCHEMBL6679372 | 0.85 | BACE1 (0.39) | ADRB3ADRB1BACE1 | |
| SCHEMBL6554211 | 0.84 | BACE1 (0.40) | ADRB3ADRB1BACE1 | |
| SCHEMBL6541553 | 0.84 | BACE1 (0.40) | ADRB3ADRB1BACE1 | |
| SCHEMBL6541560 | 0.84 | BACE1 (0.40) | ADRB3ADRB1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004045610-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2004-06-03 | — | — | WO | disclosed |