Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 12/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677330 | 1.00 | ITGB1 (0.41) | ITGB1ITGA4BACE1ADRB3ADRB1 | |
| SCHEMBL6676157 | 0.89 | BACE1 (0.36) | ITGB1ITGA4BACE1ADRB3ADRB1 | |
| SCHEMBL6801019 | 0.89 | BACE1 (0.36) | ITGB1ITGA4BACE1ADRB3ADRB1 | |
| SCHEMBL6540394 | 0.89 | ADRB3 (0.49) | BACE1ADRB3ADRB1ADRB2CYP2D6 | |
| SCHEMBL6540398 | 0.89 | ADRB3 (0.49) | BACE1ADRB3ADRB1ADRB2CYP2D6 | |
| SCHEMBL6678552 | 0.85 | BACE1 (0.39) | ITGB1ITGA4BACE1ADRB3ADRB1 | |
| SCHEMBL6678556 | 0.85 | BACE1 (0.39) | ITGB1ITGA4BACE1ADRB3ADRB1 | |
| SCHEMBL6676356 | 0.84 | BACE1 (0.39) | ITGB1ITGA4BACE1ADRB3ADRB1 | |
| SCHEMBL6804352 | 0.84 | BACE1 (0.39) | ITGB1ITGA4BACE1ADRB3ADRB1 | |
| SCHEMBL6803105 | 0.84 | BACE1 (0.39) | ITGB1ITGA4BACE1ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040106653-A1 | Aminoalcohol derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-03 | — | — | US | disclosed |
| WO-2004045610-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2004-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106653-A1 | Aminoalcohol derivatives | FANCD2, FANCI, HRH2 | ITGB1 1912/4885ITGA4 2143/4885BACE1 4413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.