Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | LPL | P06858 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5988446 | 1.00 | TP53 (0.59) | TP53CYP3A4TDP1ESR1ESR2 | |
| Iodide SCHEMBL11347856 | 0.98 | TP53 (0.56) | TP53CYP3A4TDP1ESR1ESR2 | |
| SCHEMBL150534 | 0.90 | TP53 (0.48) | TP53CYP3A4TDP1CYP2A6ALDH1A1 | |
| SCHEMBL20873234 | 0.89 | TP53 (0.52) | TP53CYP3A4TDP1ESR1ESR2 | |
| SCHEMBL15201702 | 0.87 | TP53 (0.50) | TP53CYP3A4TDP1ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL5430697 | 0.85 | TP53 (0.43) | TP53TDP1CYP2A6ALDH1A1CA2 | |
| SCHEMBL6449447 | 0.82 | CYP3A4 (0.67) | TP53CYP3A4TDP1ESR1ESR2 | |
| SCHEMBL2154162 | 0.82 | TP53 (0.54) | TP53CYP2A6ALDH1A1CYP1A2CA2 | |
| SCHEMBL15655985 | 0.82 | CYP3A4 (0.52) | TP53CYP3A4TDP1ESR1ESR2 | |
| SCHEMBL2153918 | 0.82 | TP53 (0.54) | TP53CYP3A4TDP1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048463-A1 | POLYMERIC COMPOSITIONS RAPIDLY HEATABLE UNDER ELECTROMAGNETIC IRRADIATION, THEIR USES AND PROCESSING METHODS | PARODI FABRIZIO (IT) | 2004-06-10 | — | — | WO | claimed |
| EP-3802554-B1 | METHOD FOR SOLUTION-PHASE PEPTIDE SYNTHESIS AND PROTECTING STRATEGIES THEREFORE | SEDERMA SA (FR) | 2023-12-13 | — | — | EP | disclosed |
| WO-2004048463-A1 | POLYMERIC COMPOSITIONS RAPIDLY HEATABLE UNDER ELECTROMAGNETIC IRRADIATION, THEIR USES AND PROCESSING METHODS | PARODI FABRIZIO (IT) | 2004-06-10 | — | — | WO | disclosed |
| EP-0994883-B1 | PRODUCTION OF ALKALI METAL DIARYLPHOSPHIDE AND CYCLOALKYLDIARYLPHOSPHINES | ALBEMARLE CORP (US) | 2002-09-04 | — | — | EP | disclosed |
| EP-0994883-A1 | PRODUCTION OF ALKALI METAL DIARYLPHOSPHIDE AND CYCLOALKYLDIARYLPHOSPHINES | ALBEMARLE CORPORATION (US) | 2000-04-26 | — | — | EP | disclosed |
| US-5866720-A | Production of high purity alkali metal diarylphosphide and cycloalkyldiarylphosphines | ALBEMARLE CORPORATION (US) | 1999-02-02 | — | — | US | disclosed |
| WO-1999001461-A1 | PRODUCTION OF ALKALI METAL DIARYLPHOSPHIDE AND CYCLOALKYLDIARYLPHOSPHINES | ALBEMARLE CORPORATION (US) | 1999-01-14 | — | — | WO | disclosed |
| US-5777169-A | Production of high purity alkali metal diarylphosphide and cycloalkyldiarylphosphines | ALBEMARLE CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-4472319-A | Preparation of unsaturated nitriles using a surfactant | PHILLIPS PETROLEUM COMPANY (US) | 1984-09-18 | — | — | US | disclosed |
| US-4255352-A | TANK REACTORS IN SERIES | PHILLIPS PETROLEUM COMPANY (US) | 1981-03-10 | — | — | US | disclosed |
| US-4218394-A | FROM UNSATURATED NITRILES AND OLEFINS | PHILLIPS PETROLEUM COMPANY (US) | 1980-08-19 | — | — | US | disclosed |
| US-4217303-A | UNSATURATED HYDROCARBON, ADDUCT, UNSATURATED DINITRILE, BY-PRODUCT INHIBITION | PHILLIPS PETROLEUM COMPANY (US) | 1980-08-12 | — | — | US | disclosed |
| US-4200586-A | Inhibiting the carbon-carbon double bond isomerization of substituted or unsubstituted hydrocarbon compounds | PHILLIPS PETROLEUM COMPANY (US) | 1980-04-29 | — | — | US | disclosed |
| US-3996262-A | Method of promoting the reaction of unsaturated nitriles with olefins to produce unsaturated nitriles of increased carbon number | PHILLIPS PETROLEUM COMPANY (US) | 1976-12-07 | — | — | US | disclosed |
| US-3985786-A | REACTING AN OLEFINICALLY UNSATURATED NITRILE, AN OLEFINIC HYDROCARBON AND THEIR MONOADDUCT IN WATER | PHILLIPS PETROLEUM COMPANY (US) | 1976-10-12 | — | — | US | disclosed |