Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 8/20 | 0.41 |
| ▸ | ESR1 | P03372 | 6/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 5/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3054783 | 1.00 | ESR2 (0.41) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL11331114 | 0.95 | ESR2 (0.38) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL11331112 | 0.95 | ESR2 (0.38) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL11210597 | 0.91 | ESR2 (0.47) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL11210601 | 0.91 | ESR2 (0.47) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL10935701 | 0.85 | ESR2 (0.43) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL11217896 | 0.85 | ESR2 (0.43) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL10904861 | 0.85 | ESR2 (0.43) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL10935713 | 0.85 | ESR2 (0.43) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL11217898 | 0.85 | ESR2 (0.43) | ESR2ESR1CYP2C9CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62181262-A | — | — | None | — | — | JP | disclosed |
| JP-58208241-A | — | — | None | — | — | JP | disclosed |
| CN-106967443-A | The preparation method of alkyl cyclohexyl biphenyl nitrile liquid-crystal compounds | 烟台德润液晶材料有限公司 | 2017-07-21 | — | — | CN | disclosed |
| EP-0893423-B1 | LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES | CHISSO CORP (JP) | 2004-09-01 | — | — | EP | disclosed |
| EP-0893423-A1 | LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES | CHISSO CORPORATION (JP) | 1999-01-27 | — | — | EP | disclosed |
| JP-S62181262-A | LIQUID CRYSTAL COMPOUND | SEIKO EPSON CORP | 1987-08-08 | — | — | JP | disclosed |
| JP-S58208241-A | PREPARATION OF 4,4'-BIS-(TRANS-4-ALKYLCYCLOHEXYL)-BIPHENYL COMPOUND | HAMASAWA KOGYO:KK | 1983-12-03 | — | — | JP | disclosed |
| EP-0030277-B1 | PARTIALLY HYDROGENATED OLIGO-1,4-PHENYLENES, DIELECTRICS CONTAINING THEM AND ELECTRO-OPTICAL INDICATING DEVICE | MERCK PATENT GmbH (DE) | 1983-07-27 | — | — | EP | disclosed |
| US-4331552-A | Liquid crystalline, partially hydrogenated oligo-1,4-phenylenes and dielectrics and electro-optical display elements containing them | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-05-25 | — | — | US | disclosed |
| EP-0030277-A1 | Partially hydrogenated oligo-1,4-phenylenes, dielectrics containing them and electro-optical indicating device | MERCK PATENT GmbH (DE) | 1981-06-17 | — | — | EP | disclosed |