Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 17/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 13/20 | 0.40 |
| ▸ | BACE1 | P56817 | 3/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6801134 | 1.00 | ADRB3 (0.40) | ADRB3ADRB1BACE1ADRB2 | |
| SCHEMBL6810256 | 0.95 | ADRB3 (0.40) | ADRB3ADRB1BACE1ADRB2 | |
| SCHEMBL6810261 | 0.95 | ADRB3 (0.40) | ADRB3ADRB1BACE1ADRB2 | |
| SCHEMBL6680732 | 0.94 | ADRB3 (0.39) | ADRB3ADRB1BACE1 | |
| SCHEMBL6809680 | 0.94 | ADRB3 (0.39) | ADRB3ADRB1BACE1 | |
| SCHEMBL6683357 | 0.93 | BACE1 (0.39) | ADRB3ADRB1BACE1ADRB2 | |
| SCHEMBL6680602 | 0.93 | BACE1 (0.39) | ADRB3ADRB1BACE1ADRB2 | |
| SCHEMBL6677479 | 0.92 | BACE1 (0.40) | ADRB3ADRB1BACE1 | |
| SCHEMBL6805602 | 0.92 | BACE1 (0.40) | ADRB3ADRB1BACE1 | |
| SCHEMBL6676378 | 0.92 | BACE1 (0.40) | ADRB3ADRB1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040106653-A1 | Aminoalcohol derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-03 | — | — | US | disclosed |
| WO-2004045610-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2004-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106653-A1 | Aminoalcohol derivatives | FANCD2, FANCI, HRH2 | ADRB3 150/4885ADRB1 39/4885BACE1 4413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.